Adhesion Molecules in Cerebrovascular Diseases
نویسندگان
چکیده
منابع مشابه
Inflammatory cell adhesion molecules in ischemic cerebrovascular disease.
BACKGROUND In this review we discuss the role of inflammatory cell adhesion molecules (CAMs) in ischemic stroke and in delayed cerebral ischemia after subarachnoid hemorrhage. Vascular endothelial cells and leukocytes express several inflammatory adhesion receptors, the most important of which are the selectins, immunoglobulin gene superfamily CAMs, and beta2 integrins. They mediate the transmi...
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BACKGROUND AND PURPOSE Adhesion molecules mediate attachment and transendothelial migration of leukocytes as a critical step in pathogenesis of atherosclerosis. Their expression and release were comparatively investigated in patients with large- and small-vessel disease of the central nervous system. METHODS With immunological methods, serum concentrations of endothelial-derived adhesion mole...
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Background: Inflammation is involved in development, progression, and complications of atherosclerotic disease. Clinical studies have indicated that the level of monocyte chemoattractant protein 1 (MCP-1), IL-18, and adhesion molecules correlates with the severity of atherosclerosis and can predict future cardiovascular events. Experimental studies have shown pentoxifylline (PTX) reduces these ...
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E ven by clinical and histologic findings alone it is reasonable to suspect that the pathogenesis of certain blistering skin diseases might involve abnormalities in adhesion structures. The best defined buUous diseases in this regard are pemphigus (of which there are two basic types: vulgaris and foliaceus) and bullous pemphigoid (BP) (1-3). Histology shows that the blisters in pemphigus result...
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For many years the vascular endothelium was believed simply to provide a passive lining between circulating blood and extravascular tissue. It is now clear, however, that this monolayer of cells on the luminal surface of all blood vessels, provides a selective barrier that responds dynamically to various stimuli, and controls a complex series of cellular reactions and interactions. The current ...
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ژورنال
عنوان ژورنال: Stroke
سال: 1999
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.30.8.1647